Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
A systematic review synthesizing retrospective and prospective evidence to inform clinical decision-making about locoregional surgery in de-novo stage IV breast cancer, concluding routine surgery is not recommended except for bone-only metastases.
Single-centre retrospective study of 141 patients with observational outcomes; no randomised comparator, no prospective design, and no hard clinical endpoints with effect sizes reported.
Cross-sectional survey in a single district with low absolute prevalence (10%), descriptive bacterial identification, and risk factor analysis without adjustment for multiple comparisons or external validation.
A single clinical case report describing an unusual diagnostic presentation; raises awareness of a rare mimicry but provides no generalizable evidence about incidence, diagnosis, or management.
Expert consensus panel review synthesizing literature on disease-specific management of invasive lobular carcinoma, providing multidisciplinary recommendations without presenting new primary data.
Single case report documenting an unusual metastatic pattern and therapeutic response; raises mechanistic questions about lymphatic spread and HER2 conversion but lacks comparative data or generalizable evidence.
Journal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi Dergisi
A single-patient case report with no control group, showing clinical response to combination therapy in a rare presentation; raises questions about ribociclib efficacy in visceral crisis but cannot establish causation or generalizability.
Large prospective cohort study with detailed pre-diagnostic risk factor assessment and breast density measurement in a UK screening population, yielding clear odds ratios for interval cancer risk across multiple independent variables.