Esophageal Cancer Research and Treatment

SEP 15, 2026 · JOURNAL ARTICLE

The Effect of Lymph Node Status on Clinical Examination and After Neoadjuvant Therapy and Surgery (cN and ypN) on Long-Term Outcomes in Patients with Locally Advanced Gastric Cancer

Voprosy Onkologii

The source record carries too little text to support an evidence assessment.

SEP 9, 2026 · REVIEW

Survival benefit and toxicity trade-offs of first-line chemoimmunotherapy in advanced gastric and gastroesophageal junction cancer: a meta-analysis of randomized trials

Frontiers in Oncology

A high-quality meta-analysis of 7 RCTs with 6,517 patients showing consistent survival and response benefit for chemoimmunotherapy, but with quantified and clinically relevant toxicity trade-offs that require individualised patient selection.

SEP 9, 2026 · JOURNAL ARTICLE

Gastric Mucosa Cancer Risk: The Operative Link on Gastritis Assessment Staging System

The Korean Journal of Helicobacter and Upper Gastrointestinal Research

A narrative review synthesizing evidence on gastric atrophy staging and risk stratification to inform clinical surveillance strategy and serological monitoring in individual patients.

SEP 8, 2026 · JOURNAL ARTICLE

Metabolic predictors of response to immunotherapy in locally advanced or metastatic esophageal cancer: unveiling the obesity paradox

Scientific Reports

A sound retrospective cohort study with internal and external validation showing that high BMI predicts superior immunotherapy outcomes in esophageal cancer, but limited by observational design, modest sample size, and reliance on surrogate endpoints rather than hard clinical outcomes.

SEP 7, 2026 · JOURNAL ARTICLE

Do not try this at home: patterns and outcomes of radiation dose de-escalation in p16-positive oropharyngeal carcinoma

Frontiers in Oncology

Large national cohort study with hard clinical outcome (overall survival) showing inferior outcomes with dose de-escalation, aligning with recent randomized evidence and supporting current standard-of-care dosing.

SEP 7, 2026 · JOURNAL ARTICLE

Surgical management of small bowel metastasis from esophageal squamous cell carcinoma: a case report and literature review

Frontiers in Surgery

A single case report with clinical narrative describing an unusual metastatic pattern; it raises mechanistic hypotheses and clinical management questions but provides no comparative data, control group, or generalizable evidence.

SEP 6, 2026 · JOURNAL ARTICLE

Prophylactic treatment of regional lymph drainage zones in stage T1–2N0M0 oral cavity cancer: a retrospective population-based analysis

South Russian Journal of Cancer

Rigorous population-based retrospective cohort study with multivariable adjustment comparing four treatment strategies in localized oral cavity cancer, demonstrating significantly improved survival with elective neck dissection versus omission or radiotherapy alone.

SEP 5, 2026 · JOURNAL ARTICLE

Comparative efficacy and safety of neoadjuvant and perioperative systemic therapies for resectable locally advanced gastric and gastroesophageal junction adenocarcinoma: a network meta analysis of randomized controlled trials

BMC Gastroenterology

Network meta-analysis of 36 RCTs with 8925 patients comparing defined treatment classes for resectable locally advanced gastric cancer, with consistent superiority of chemotherapy plus immunotherapy across survival and pathological endpoints, but limited by indirect comparisons and heterogeneous trial populations.