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Luohong Li

Sichuan University

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SEP 5, 2026 · JOURNAL ARTICLE

Comparative efficacy and safety of neoadjuvant and perioperative systemic therapies for resectable locally advanced gastric and gastroesophageal junction adenocarcinoma: a network meta analysis of randomized controlled trials

BMC Gastroenterology

Network meta-analysis of 36 RCTs with 8925 patients comparing defined treatment classes for resectable locally advanced gastric cancer, with consistent superiority of chemotherapy plus immunotherapy across survival and pathological endpoints, but limited by indirect comparisons and heterogeneous trial populations.

Strong EvidenceLuohong Li Junli Zhang Esophageal Cancer Research and Treatment

Reported

Total patients enrolled8925

Trials contributing to OS15

Trials contributing to pCR18

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