Cancer Risks and Factors

SEP 9, 2026 · JOURNAL ARTICLE

Rationale and design of the: breast cancer, fitness and exercise for heart health (BE-FITTER trial)

Cardio-oncology

This is a rationale-and-design paper for a small, single-centre RCT that has not yet reported results; it describes planned methods and hypotheses rather than outcomes.

SEP 8, 2026 · JOURNAL ARTICLE

Metabolic predictors of response to immunotherapy in locally advanced or metastatic esophageal cancer: unveiling the obesity paradox

Scientific Reports

A sound retrospective cohort study with internal and external validation showing that high BMI predicts superior immunotherapy outcomes in esophageal cancer, but limited by observational design, modest sample size, and reliance on surrogate endpoints rather than hard clinical outcomes.

SEP 5, 2026 · JOURNAL ARTICLE

Integrated analysis reveals the impact of obesity on triple-negative breast cancer

Cancer Letters

Integrated multi-omics analysis in a large single-centre TNBC cohort with mechanistic mouse experiments and supportive clinical trial data, but observational design, no randomized comparator, and reliance on retrospective trial analysis limit definitive claims about causation or clinical practice change.

SEP 4, 2026 · JOURNAL ARTICLE

Nutritional Status of Patients with Cancer During Oncological Treatment—A Multicenter Cross-Sectional Study

Nutrients

Cross-sectional survey of nutritional status in cancer patients using validated screening tools; descriptive prevalence findings without a comparator group, control arm, or analytical testing of interventions.

AUG 18, 2026 · JOURNAL ARTICLE

Effect of BMI on efficacy of androgen receptor pathway inhibitors in patients with metastatic hormone-sensitive prostate cancer

Journal of Oncology Pharmacy Practice

Retrospective cohort study of 330 patients reporting an obesity paradox in mHSPC; confirms known associations but BMI did not retain independent significance in multivariate analysis, limiting practice implications.

AUG 18, 2026 · JOURNAL ARTICLE

Circulatory and other-cause mortality after neoadjuvant versus adjuvant chemotherapy in women with stage II–III breast cancer

Biomolecules and Biomedicine

A large, well-designed retrospective cohort study with robust methods (inverse-probability weighting, competing-risks analysis) that confirms the absence of a clinically meaningful difference in circulatory mortality between treatment sequences, with narrow confidence intervals crossing the null.

AUG 17, 2026 · JOURNAL ARTICLE

Beyond Weight Loss: A Comprehensive Review of Integrated Pharmacotherapy and Metabolic Bariatric Surgery in Endometrial Cancer Care

Medicina

A narrative review synthesizing evidence on metabolic interventions for endometrial cancer in obesity, offering clinical recommendations but explicitly acknowledging gaps in prospective evidence for oncologic outcomes.

AUG 15, 2026 · JOURNAL ARTICLE

Obesity at antiretroviral therapy initiation and long-term risk of cardiovascular disease, cancer, or death in people with HIV in Italy: a prospective cohort study

Eclinicalmedicine

Prospective cohort study with adequate sample size and hard clinical outcomes (CVD, cancer, death), but unadjusted effect is attenuated to borderline significance after adjustment (aHR 1.28, 95% CI 0.98–1.67, p=0.073), limiting definitive causal inference.