Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
European Journal of Nuclear Medicine and Molecular Imaging
External validation of an established prognostic score in an independent cohort, demonstrating reproducibility of risk stratification and survival prediction with robust performance metrics, but not introducing new clinical intervention or changing treatment selection.
A single-centre algorithm development study demonstrating proof-of-concept for CNN-based prostatectomy detection on CT with reasonable accuracy, but lacking external validation, clinical outcomes data, and prospective deployment evidence.
This is a narrative review synthesizing observational associations and mechanistic hypotheses about the gut–prostate axis without reporting original trial data, causal evidence, or effect sizes.
A retrospective single-centre analysis of metastasis-directed SBRT in oligo-recurrent prostate cancer showing feasible local control and delayed systemic therapy, but lacking a comparator and prospective design.
Descriptive comparative immunohistochemistry study raising mechanistic questions about CREB phosphorylation regulation in primate versus human prostate tissue, without clinical outcome data or functional validation.
Large real-world retrospective cohort with prospectively collected data, clear PSA endpoints, and adjusted analysis demonstrating consistent superiority of ARSI-based regimens over ADT monotherapy in mCSPC, though limited by surrogate endpoints and lack of hard clinical outcomes.
A narrative review synthesizing epidemiological, clinical, and experimental literature to propose a conceptual framework linking metabolic syndrome and chronic inflammation to BPH pathogenesis and treatment response.
Retrospective cohort study with clear associations between PSA dynamics, metastatic status and time to progression, but limited by single-country setting, lack of multivariate adjustment, and no comparison group receiving alternative therapy.