Prostate Cancer Treatment and Research

SEP 10, 2026 · JOURNAL ARTICLE

Patterns of Health Care Spending in Prostate Cancer

JAMA Network Open

A descriptive economic analysis of spending patterns using administrative data; documents trends but lacks comparative design, causal inference, or clinical outcomes to support practice change.

SEP 9, 2026 · JOURNAL ARTICLE

Dicloreto de rádio-223 no câncer de próstata resistente à castração com metástases ósseas: relato de caso clínico e implicações terapêuticas para medicina nuclear

Revista Fisio&terapia.

A single uncontrolled case report with laboratory monitoring but no efficacy endpoint, comparator, or outcome data; raises clinical questions but does not answer them.

SEP 9, 2026 · JOURNAL ARTICLE

Minimal-length CAG repeats in AR define a hyperactive AR–LSD1 axis driving metabolic reprogramming in prostate cancer

Proceedings of the National Academy of Sciences

Cell line study identifying a mechanistic link between AR CAG repeat polymorphism and metabolic reprogramming; lacks in vivo validation, patient outcome data, or clinical endpoint evidence.

SEP 8, 2026 · JOURNAL ARTICLE

External validation of the bellmunt risk score for survival prediction in mCRPC patients undergoing [177Lu]Lu-PSMA-617 therapy

European Journal of Nuclear Medicine and Molecular Imaging

External validation of an established prognostic score in an independent cohort, demonstrating reproducibility of risk stratification and survival prediction with robust performance metrics, but not introducing new clinical intervention or changing treatment selection.

SEP 8, 2026 · JOURNAL ARTICLE

Organ and tumor dosimetry of [161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC

European Journal of Nuclear Medicine and Molecular Imaging

First dosimetry characterization of 161Tb-PSMA-617 in a small, uncontrolled registry cohort without clinical outcome data, providing absorbed dose estimates but lacking efficacy, safety or comparative evidence.

SEP 7, 2026 · JOURNAL ARTICLE

Lutetium-177 radiopharmaceuticals in cancer care: progress and challenges

Frontiers in Pharmacology

A narrative review synthesizing clinical trial evidence, regulatory approvals, and translational findings to propose a strategic framework for advancing Lu-177 radiopharmaceutical therapy, rather than reporting a primary empirical result.

SEP 7, 2026 · JOURNAL ARTICLE

Bridging to systemic therapy: PSMA-PET-based early and repetitive stereotactic body radiotherapy for nodal and bone oligo-recurrent prostate cancer

Frontiers in Urology

A retrospective single-centre analysis of metastasis-directed SBRT in oligo-recurrent prostate cancer showing feasible local control and delayed systemic therapy, but lacking a comparator and prospective design.

SEP 7, 2026 · JOURNAL ARTICLE

Comparative analysis of prostate glands of non-human primates and men shows increased cell-autonomy of CREB phosphorylation in prostatectomies

Scientific Reports

Descriptive comparative immunohistochemistry study raising mechanistic questions about CREB phosphorylation regulation in primate versus human prostate tissue, without clinical outcome data or functional validation.