Background Musculoskeletal manifestations may appear before hematologic abnormalities in childhood acute lymphoblastic leukemia (ALL), making diagnosis difficult. Extensive vertebr
Childhood obesity-related metabolic complications are common in Northwest China, yet region-specific evidence and risk-stratification tools are lacking. In a single-visit cross-sec
Background Acute leukemia (AL) is the most common malignancy in childhood. Despite significant improvements in survival rates, long-term high-intensity chemotherapy often leads to
Background Meridian-based traditional Chinese medicine (TCM) interventions are increasingly used as adjunctive approaches to manage treatment-related toxicities in children, adoles
Cross-sectional observational study establishing reference data and associations in a single geographic region; hypothesis-generating findings on vitamin K and precocious puberty that cannot establish causation and require prospective validation.
A small, single-centre descriptive comparison of two obesity classification methods in a specific transplant population, with a primary finding (BMI possibly overestimating obesity) that did not reach statistical significance and requires confirmation.
A narrative expert consensus and framework paper outlining One Health principles and digital transformation priorities for pediatric infectious disease practice, rather than reporting original research evidence.
Small cross-sectional study with a null primary finding in a novel biomarker; design and execution are sound but the negative result in a limited sample does not yet establish absence of association.