Dialysis and Renal Disease Management

SEP 7, 2026 · JOURNAL ARTICLE

Aerobic Exercise Ameliorates Renal Injury in High‐Fat Diet‐Fed Mice: A Novel Effect Mediated by the Drp1‐mtROS Pathway

Acta Physiologica

A mechanistic study in mice and cultured cells demonstrating aerobic exercise reduces renal injury via Drp1-mtROS inhibition; the pathway is novel and supported by consistent findings across models, but lacks direct clinical validation and hard renal outcomes.

SEP 7, 2026 · JOURNAL ARTICLE

Gut microbial phenol impairs energy metabolism and promotes sarcopenic obesity-like phenotypes in mice

Scientific Reports

A mechanistic, preclinical mouse study raising a question about phenol's role in metabolism and body composition; findings need confirmation in humans and disease models.

AUG 22, 2026 · JOURNAL ARTICLE

Thromboembolic prophylaxis in kidney failure patients with atrial fibrillation undergoing hemodialysis: from risk stratification to decision making on anticoagulants or left atrial appendage closure. A position paper endorsed by the Italian Society of Nephrology

Journal of Nephrology

This is a position paper endorsed by the Italian Society of Nephrology that synthesizes evidence on anticoagulation and LAAC in a specific population, providing recommendations where RCT evidence is absent.

AUG 11, 2026 · JOURNAL ARTICLE

Cystatin C: Not Only a Kidney Marker but Also a Potential Early Indicator of Metabolic Alterations in Childhood Obesity

Hormone Research in Paediatrics

A sound cross-sectional study in a focused population showing independent associations between cystatin C and measures of adiposity and insulin resistance, but limited by retrospective design, lack of prospective validation, and surrogate endpoints.

AUG 11, 2026 · JOURNAL ARTICLE

Assessment of Renal Diseases Associated with Obesity in a Tertiary Care Hospital

Eastern Medical College Journal

Single-centre, small prospective cross-sectional study (n=53) with no comparator group; describes prevalence of renal findings in an obese population but lacks the design rigour and sample size to establish causation or guide practice change.

AUG 7, 2026 · JOURNAL ARTICLE

Insulin resistance as a potential mediator between central obesity and diabetic kidney disease risk in type 2 diabetes

Scientific Reports

Cross-sectional study with a large community sample demonstrating that central obesity associates with DKD risk via insulin resistance as a partial mediator, but causality cannot be inferred and the effect is attenuated by metabolic adjustment.

AUG 6, 2026 · JOURNAL ARTICLE

Cardiovascular-Kidney-Metabolic Conditions and Population Health

Clinical Journal of the American Society of Nephrology

This is a narrative review proposing a framework for integrated care programs in CKM syndrome, grounded in existing evidence of efficacy from RCTs but presenting expert recommendation rather than new primary data.