Dialysis and Renal Disease Management / Chronic Kidney Disease and Diabetes / Renal Transplantation Outcomes and Treatments · Journal article
Frontiers in Pediatrics · September 9, 2026
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This is a small cross-sectional study comparing body fat percentage versus BMI for obesity classification in 35 adolescent and young adult kidney transplant recipients. BMI classified 42.9% as overweight/obese compared to 28.6% by body fat percentage, but this difference did not reach statistical significance (p = 0.125), and the authors acknowledge the sample size was insufficient to confirm whether body fat percentage is a more accurate classifier in this population.
Cross-sectional comparative study. 35 kidney transplant recipients (18 females, 17 males; mean age 19.5 ± 2.5 years) attending a KT transition clinic; 54.3% had hypertension and 25.7% had metabolic syndrome.. Intervention: Body fat percentage measurement via bioelectrical impedance analysis. Compared with: Body mass index-based obesity classification. n = 35. Not stated.
BMI classified 42.9% [95% CI: 28.0–59.1%] as overweight/obese versus 28.6% [95% CI: 16.3–45.1%] by %BF (McNemar p = 0.125) %BF significantly higher in females (30.1 ± 6.1%) than males (23.3 ± 7.9%; p < 0.01) BMI–%BF correlation stronger in males (r = 0.903) than females (r = 0.777)
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This pilot study raises the question of whether body fat percentage might be a more sex-appropriate classifier than BMI in young transplant recipients, but the difference did not achieve statistical significance and the findings require confirmation in a larger cohort. Clinicians should not change practice based on this result alone.
A small, single-centre descriptive comparison of two obesity classification methods in a specific transplant population, with a primary finding (BMI possibly overestimating obesity) that did not reach statistical significance and requires confirmation.
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This pilot study raises the question of whether body fat percentage might be a more sex-appropriate classifier than BMI in young transplant recipients, but the difference did not achieve statistical significance and the findings require confirmation in a larger cohort. Clinicians should not change practice based on this result alone.
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Purpose Obesity is defined by body mass index (BMI), a poor marker of adiposity that does not take into account sex differences. It was recently shown in a large database of adults that percentage of body fat (%BF) can also be used to define clinically relevant overweight/obese status with sex-specific cut-offs. This definition was never tested in adolescent and young adult (AYA) kidney transplant (KT) recipients. Methods We compared the %BF method of defining obesity with the BMI-based method in a population of AYAs belonging to a KT transition clinic. The %BF was measured using a total body composition scale (Body Composition Analyzer, Tanita Corporation, Tokyo) based on the bioelectrical impedance analysis. Results Thirty-five patients (18 females, 17 males; mean age 19.5 ± 2.5 years) were enrolled. Hypertension was present in 54.3%; metabolic syndrome in 25.7%. BMI classified 42.9% [95% CI: 28.0–59.1%] as overweight/obese vs. 28.6% [95% CI: 16.3–45.1%] by %BF (McNemar p = 0.125). %BF was significantly higher in females (30.1 ± 6.1%) than males (23.3 ± 7.9%; p < 0.01). BMI–%BF correlation was stronger in males ( r = 0.903) than females ( r = 0.777). Conclusions Overweight and obesity were common in KT AYA recipients. Cardiovascular risks are common. The BMI-based method appeared to possibly overestimate obesity, although statistical significance was not attained, likely due to the small sample size. Further studies are needed to confirm if %BF is more accurate in determining obesity compared to BMI in this population.
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