Chinese Academy of Medical Sciences & Peking Union Medical College
2 developments in the corpus
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A mechanistic study in mice and cultured cells demonstrating aerobic exercise reduces renal injury via Drp1-mtROS inhibition; the pathway is novel and supported by consistent findings across models, but lacks direct clinical validation and hard renal outcomes.
Rigorous prospective cohort study with adjudicated hard cardiovascular endpoints, clear phenotype-based risk stratification with internal and external validation, showing clinically meaningful hazard ratios that outperform standard AHI scoring.