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A narrative review article synthesizing current knowledge and future directions in CRISPR-based gene therapy for hemophilia, without reporting original empirical findings or clinical trial results.
A structured literature review synthesizing current evidence on CRISPR-Cas9 therapeutic applications, identifying clinical advances, translational hurdles, and emerging alternatives without reporting original trial data or effect sizes.
This is a narrative review of CRISPR-Cas9 delivery concepts for bladder cancer therapy with no original experimental data, clinical trial results, or comparative evidence.
A comprehensive narrative review synthesizing mechanistic knowledge, detection methods, and safety mitigation strategies for off-target effects across CRISPR platforms—intended to inform clinical development and standardization rather than to report original data.
A narrative review synthesizing recent advances in CRISPR delivery strategies across research and clinical contexts, offering state-of-the-art overview rather than novel empirical evidence or recommendations.
A prospective multicenter clinical evaluation demonstrating 100% sensitivity for S. aureus detection in 350 patients with suspected bacteremia, but limited by small MRSA case numbers (n=8) and lack of specificity data, requiring confirmation in larger MRSA-enriched cohorts before clinical implementation.
A narrative review of preclinical and mechanistic studies proposing CRISPR-Cas13 as a therapeutic concept for HIV remission, without clinical trial data or definitive evidence of durable clinical benefit.
A narrative review of preclinical literature synthesizing nanocarrier design and CRISPR delivery mechanisms, raising research directions rather than reporting original empirical evidence or clinical outcomes.