RNA Interference and Gene Delivery

SEP 9, 2026 · JOURNAL ARTICLE

Recent advances in delivery strategies for CRISPR-based genome editing

Molecular Medicine

A narrative review synthesizing recent advances in CRISPR delivery strategies across research and clinical contexts, offering state-of-the-art overview rather than novel empirical evidence or recommendations.

SEP 8, 2026 · JOURNAL ARTICLE

mRNA therapeutics in cancer: from molecular design to clinical translation

Molecular Cancer

A comprehensive review synthesizing the state of mRNA cancer therapeutics across design, delivery, and clinical translation—expert framing rather than a new empirical finding.

SEP 8, 2026 · JOURNAL ARTICLE

Sequential Precise Targeted Hepatitis B Virus Therapy: Hepatitis B Virus-Specific Small Interfering RNA Followed by Aggregation-Induced Emission-Photothermal Ablation Based on Macrophage Membrane-Coated Nanoplatform

Acs Applied Bio Materials

This is an exploratory in vitro proof-of-concept study of a novel nanoplatform combining siRNA and photothermal therapy; it demonstrates mechanism in cell models but lacks in vivo efficacy data, clinical translation, or direct comparison to standard antiviral therapy.

SEP 8, 2026 · JOURNAL ARTICLE

Nanocarrier-Mediated Gene Editing for Improved Tumour Therapeutic Efficacy

Theoretical and Natural Science

A narrative review of preclinical literature synthesizing nanocarrier design and CRISPR delivery mechanisms, raising research directions rather than reporting original empirical evidence or clinical outcomes.

SEP 7, 2026 · JOURNAL ARTICLE

Aptamer-Functionalized Liposomes for Targeted Delivery of Anticancer Drugs in Lung Cancer

Molecules

Early-phase in vitro characterization of a novel drug delivery system in cell lines; demonstrates proof-of-concept but lacks in vivo validation, clinical endpoints, or comparison to standard therapies.

SEP 5, 2026 · JOURNAL ARTICLE

Engineering microRNAs as multimodal cancer therapeutics

Molecular Therapy — Nucleic Acids

This is a commentary describing a novel preclinical approach to engineer microRNAs as cancer therapeutics; it reports no original experimental data, effect sizes, or clinical outcomes.

SEP 1, 2026 · JOURNAL ARTICLE

Target, silence, replace: a review on RNA-based drugs in modern medicine

Frontiers in Cell and Developmental Biology

A comprehensive narrative review synthesizing mechanisms, delivery strategies, and clinical applications of multiple RNA therapeutic modalities, not a primary empirical study.

AUG 30, 2026 · JOURNAL ARTICLE

Recent Advances in Non-Viral Vectors for Gene Therapy and Gene Delivery: From Lipid Nanoparticles to Engineered Extracellular Vesicles

Pharmaceutics

This is a narrative review summarizing the state of non-viral gene delivery platforms, their clinical maturity, barriers, and future directions for researchers and clinicians.