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A comprehensive review synthesizing the state of mRNA cancer therapeutics across design, delivery, and clinical translation—expert framing rather than a new empirical finding.
Unrefereed computational methods paper on machine learning optimization; no clinical trial data, human subjects, or peer-reviewed publication status reported.
Retrospective cohort study with rigorous time-dependent Cox analysis addressing immortal time bias, demonstrating independent OS benefit of cutaneous irAE in advanced NSCLC, but single-institution design and small grade 3+ subgroup limit immediate generalizability.
This is a narrative review summarizing design strategies and emerging biomaterial approaches for osteomyelitis; it raises questions about clinical translation rather than reporting new evidence or trials.