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A small convenience-sampled cross-sectional study (n=97) in a single region identifying associations with presenteeism via survey instruments, without causal design or hard clinical outcomes, and acknowledged by authors as non-causal.
A comprehensive narrative review synthesizing mechanistic and associative evidence on glycosylation's role in gut-brain communication, identifying regulatory pathways and therapeutic opportunities but not reporting original empirical findings or clinical outcomes.
This is a methodological paper introducing a novel statistical technique with theoretical development and numerical validation, but lacks clinical or real-world application data and has not undergone peer review.
Single-cohort mechanistic study linking TCR biophysics to clonal outcomes in SARS-CoV-2 responses, with no randomization or comparator group; findings are descriptive and correlational rather than causal or predictive.