Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
Single-centre case series of 18 patients with descriptive outcomes and no comparator; generates mechanistic hypotheses about steatotic liver disease in allo-HSCT but lacks the control group and sample size needed to establish clinical impact.
Mechanistic study in animal models and cell culture demonstrating SGF efficacy against NASH through multiple pathways; results are convincing within the experimental system but require clinical translation.
A narrative review synthesizing current evidence on pediatric MASLD epidemiology, pathophysiology, diagnosis, and management, emphasizing personalized medicine approaches rather than reporting new primary research findings.
A narrative review synthesizing current evidence on immunotherapy in advanced biliary tract cancer, highlighting established standards (TOPAZ-1, KEYNOTE-966), emerging biomarkers, and investigational approaches rather than reporting original trial results.
This is a mechanistic review proposing a framework for model selection in MASH research; it raises questions about which experimental systems best interrogate specific biological pathways rather than testing a defined clinical hypothesis with empirical data.
Large population-based retrospective administrative study with robust sample size and clear epidemiologic findings, but uses diagnostic coding and medication dispensation as case identification without clinical validation, limiting causal inference and generalizability beyond Brazil's public system.
A single clinical case report with autopsy findings that illustrates a rare disease presentation; descriptive evidence useful for differential diagnosis but without comparative or interventional data.
This is a narrative review synthesizing mechanistic pathways and existing evidence rather than presenting original clinical data or trial results, raising questions about the menopause-obesity-MASH axis rather than answering them with new evidence.