Drug or technology

Hematopoietic Stem Cell Transplantation

3 developments in the corpus

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SEP 8, 2026 · JOURNAL ARTICLE

Sickle cell disease and hematopoietic stem cell transplantation: donor expansion, gene-modified grafts and prenatal horizons

Current Opinion in Hematology

This is a narrative review synthesizing recent advances in HSCT and gene-modified stem cell transplantation for sickle cell disease, offering expert perspective on current clinical benchmarks and emerging approaches rather than reporting new primary evidence.

Expert GuidanceHematopoietic Stem Cell Transplantation Prenatal Screening and Diagnostics Hemoglobinopathies and Related Disorders

Study details

DesignNarrative review

AUG 8, 2026 · JOURNAL ARTICLE

Factors influencing health-related quality of life in children with leukemia in Saudi Arabia: a cross- sectional study

BMC Pediatrics

A single-centre cross-sectional study identifying modifiable and non-modifiable factors associated with HRQoL in paediatric leukaemia using validated instruments and multivariable regression, with moderate sample size and substantial explained variance, but lacking a comparator or control group.

PromisingMohammed A Zalah Hematopoietic Stem Cell Transplantation Mohamed Emam

Reported

Mean overall HRQoL score62.7 ± 16.5

Female gender coefficientβ = 0.270, 95% CI: 4.457–13.241, p < 0.001

Older age coefficientβ = 0.229, 95% CI: 1.951–7.986, p = 0.002

JUL 15, 2026 · JOURNAL ARTICLE

Immune organoids for Africa: a roadmap for bridging the innovation gap in infectious diseases and cancer research

Journal of the Egyptian National Cancer Institute

A narrative review synthesizing evidence and expert consensus on implementing immune organoid technology in African research contexts, proposing a strategic roadmap aligned with continental health research priorities.

Expert GuidanceHematopoietic Stem Cell Transplantation Adeyemi Sallam Febilola Chinemerem Henry Ugo

Reported

DALY burden attributable to Sub-S…approximately 25%

Global health research output con…fewer than 3%

GWAS participants of African ance…fewer than 0.2%