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Cross-sectional study in a defined population showing a clear association between UHR% and ultrasound-defined fatty liver with adjustment for multiple covariates, but lacking external validation, prospective design, and hard clinical outcomes.
Cross-sectional study in a single-sex, geographically limited cohort using surrogate measures (visceral fat, liver stiffness, lipid indices) without hard clinical outcomes; findings are descriptive and hypothesis-generating rather than definitive.
This is a narrative review synthesizing current understanding of cardiovascular-kidney-metabolic syndrome and hepatic involvement, offering diagnostic and therapeutic recommendations rather than reporting original research evidence.
International Journal of Innovative Technologies in Social Science
A narrative review synthesizing disease nomenclature, pathophysiology, diagnostics, and therapeutic approaches including emerging precision medicine concepts, without reporting original clinical trial data or systematic evidence synthesis.
A narrative review synthesizing current evidence and guidelines on MASLD/MASH epidemiology, associations, and management recommendations for clinical practice.
Cross-sectional study demonstrating clear associations between CMI and hepatic enzymes and metabolic markers in overweight/obese adults, but limited by observational design and inability to establish causation.
Single-centre case series of 18 patients with descriptive outcomes and no comparator; generates mechanistic hypotheses about steatotic liver disease in allo-HSCT but lacks the control group and sample size needed to establish clinical impact.
Large, well-designed retrospective cohort study with 29,889 participants, 4,829 incident events, and 115,088 person-years of follow-up demonstrating dose-dependent associations between cumulative unfavorable eating behaviors and incident liver disease with consistent effect estimates across multiple analytical approaches.