SEP 9, 2026 · JOURNAL ARTICLE
Smilax glabra flavonoids ameliorate non-alcoholic steatohepatitis by regulating PKM2-dependent glycolysis and suppressing AIM2 inflammasome activation
Frontiers in Immunology
Mechanistic study in animal models and cell culture demonstrating SGF efficacy against NASH through multiple pathways; results are convincing within the experimental system but require clinical translation.
Reported
SGF dose range30 or 90 mg/kg/day
HFD duration and concurrent treat…20 weeks
Comparator agentempagliflozin (EMPA)