A narrative literature review synthesizing preclinical evidence on nanoparticle radiosensitizers for proton therapy; raises mechanistic questions and identifies research gaps rather than reporting new empirical results or clinical outcomes.
Drug or technology
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A narrative literature review synthesizing preclinical evidence on nanoparticle radiosensitizers for proton therapy; raises mechanistic questions and identifies research gaps rather than reporting new empirical results or clinical outcomes.
AUG 16, 2026 · JOURNAL ARTICLE
Applied Sciences
This is a narrative review examining theoretical quantum-mechanical principles and emerging technologies in radiotherapy without reporting empirical results, clinical outcomes, or comparative evidence.
AUG 15, 2026 · JOURNAL ARTICLE
Ejnmmi Physics
This is a computational methods validation study comparing three Monte Carlo codes for microdosimetry calculations; it demonstrates technical concordance but provides no clinical outcome data or patient evidence.
AUG 14, 2026 · JOURNAL ARTICLE
Frontiers in Oncology
Sound experimental study in 3D models demonstrating that DNA damage response inhibitors enhance radiosensitivity to both X-rays and proton therapy, but limited to in vitro spheroids without clinical validation or human data.
AUG 13, 2026 · JOURNAL ARTICLE
BMC Cancer
A two-phase feasibility and safety study combining dosimetric planning with retrospective clinical validation in a single institution, showing efficiency gain and acceptable acute toxicity, but limited by retrospective design, modest sample size, and surrogate endpoints.
AUG 13, 2026 · JOURNAL ARTICLE
Radiation Oncology
Single-centre feasibility study with small sample (n=20) and surrogate endpoints (dosimetric indices); demonstrates technical capability but lacks hard clinical outcomes or patient data.
AUG 13, 2026 · JOURNAL ARTICLE
Nano Today
Preclinical in vivo study of a novel nanoparticle platform demonstrating mechanistic effects on tumor hypoxia and radiosensitivity in animal models, without clinical trial data or direct comparison to standard therapy.
AUG 12, 2026 · JOURNAL ARTICLE
Physica Medica
A methodological study implementing a novel four-dimensional dosimetry algorithm in a retrospective cohort; it demonstrates technical feasibility and reports dosimetric differences but lacks clinical outcome validation or prospective design.