Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
Cell line study identifying a mechanistic link between AR CAG repeat polymorphism and metabolic reprogramming; lacks in vivo validation, patient outcome data, or clinical endpoint evidence.
A well-designed retrospective cohort study with adequate sample size demonstrating a plausible mechanistic pathway (DHEA-S mediation) between obesity and advanced bone age, but limited by single-center design, cross-sectional analysis, and surrogate endpoint (bone age ratio rather than clinical outcomes).
A prospective observational study with adequate sample size (n=325) and multivariate analysis showing associations between obesity and multiple hormonal markers in children, but lacking a comparator intervention and relying on cross-sectional associations rather than causal evidence.
A narrative review synthesizing evidence on therapeutic versus abusive AAS use and cardiovascular risk, offering multidisciplinary clinical management recommendations rather than reporting a primary study result.