Stroke

AUG 13, 2026 · OBSERVATIONAL STUDY

MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central Norway

ClinicalTrials.gov

This is a clinical trial registry record documenting a planned observational cohort study with no results yet reported; it describes study design and objectives only.

AUG 3, 2026 · JOURNAL ARTICLE

Real-world evidence on off-label underdosing of direct oral anticoagulants in Asian patients with atrial fibrillation: prescribing patterns, determinants, and outcomes.

Future Science Oa

A single-centre retrospective cohort study with modest sample size examining real-world DOAC dosing patterns and outcomes in an underrepresented Asian population; findings on safety equivalence are not powered to exclude clinically important differences.

JUL 27, 2026 · JOURNAL ARTICLE

Long-term causes of death in 888,003 ischemic stroke patients in Thailand: a nationwide retrospective study with 18-year follow-up.

Annals of Medicine

Large national retrospective cohort with 18-year follow-up describing mortality patterns in ischemic stroke; confirms known temporal shifts in cause-of-death profiles but is descriptive, not comparative, and provides no intervention effect.

JUL 2, 2026 · JOURNAL ARTICLE

Population attributable fraction of cardiovascular disease, coronary heart disease, and stroke associated with insufficient non-occupational physical activity in Iranian adults: findings from the STEPS 2021 survey.

Journal of Diabetes and Metabolic Disorders

Cross-sectional survey estimating population attributable fractions with acknowledged reverse causation bias; provides policy-relevant scenario estimates but cannot establish causality or direct clinical effects.

MAY 13, 2026 · JOURNAL ARTICLE

Comparative efficacy and safety of apixaban and rivaroxaban versus warfarin in atrial fibrillation patients with end-stage renal disease: a systematic review and meta-analysis.

Renal Failure

Meta-analysis of 3 RCTs and 8 observational studies shows apixaban and rivaroxaban associated with lower bleeding risk versus warfarin in dialysis patients with AF, but efficacy endpoints show substantial heterogeneity and RCT-only analysis lacked statistical significance; evidence is suggestive but requires dedicated large RCTs.

APR 30, 2026 · JOURNAL ARTICLE

Effect of intensive versus standard blood pressure control on cardiovascular outcomes: a meta-analysis of randomized controlled trials.

Annals of Medicine

Large meta-analysis of 31 RCTs with 156,933 participants demonstrates consistent, statistically significant reductions across multiple cardiovascular endpoints with narrow confidence intervals; evidence quality limited by heterogeneity across trials and absence of reported adverse event data.