International Journal of Medical & Pharmaceutical Sciences

SEP 7, 2026 · JOURNAL ARTICLE

Efficacy, Safety and Clinical Implications of GLP-1 Receptor Agonists for Chronic Weight Management in Patients with or Without Type 2 Diabetes

International Journal of Medical & Pharmaceutical Sciences

A narrative review synthesizing evidence from pivotal trials to evaluate GLP-1 receptor agonists for weight management, offering clinical recommendations rather than reporting original research.

SEP 7, 2026 · JOURNAL ARTICLE

Efficacy, Safety and Clinical Implications of GLP-1 Receptor Agonists for Chronic Weight Management in Patients with or Without Type 2 Diabetes

International Journal of Medical & Pharmaceutical Sciences

A narrative review synthesizing evidence from pivotal trials to provide clinical recommendations on GLP-1 agonist use for weight management, addressing efficacy, safety and individualized patient selection.

AUG 13, 2026 · JOURNAL ARTICLE

Insulin Resistance in Polyendocrine Metabolic Ovarian Syndrome: Mechanisms, Clinical Evidence, and Emerging Biomarkers

International Journal of Medical & Pharmaceutical Sciences

A narrative review synthesizing case-control and cross-sectional evidence that replicates established understanding of insulin resistance as central to PMOS pathophysiology, without new interventional trials or practice-level guidance.

AUG 4, 2026 · JOURNAL ARTICLE

Hutchinson Gilford Syndrome - Literature Review

International Journal of Medical & Pharmaceutical Sciences

A literature review synthesizing epidemiology, pathophysiology, clinical features, diagnosis and management of a rare genetic disorder, with discussion of emerging therapies but no new primary data or evidence synthesis.

AUG 4, 2026 · JOURNAL ARTICLE

Hutchinson Gilford Syndrome - Literature Review

International Journal of Medical & Pharmaceutical Sciences

A narrative literature review synthesizing existing knowledge on HGPS epidemiology, pathophysiology, and emerging therapies; descriptive in nature without primary data, controlled trials, or novel empirical findings.

JUL 19, 2026 · JOURNAL ARTICLE

A Novel Genomic Strategy Against Hyperuricemia: CRISPR-CAS9-Mediated Restoration of Uricase Function from the Human Pseudogene

International Journal of Medical & Pharmaceutical Sciences

First-in-human cell culture demonstration of CRISPR-mediated uricase gene restoration with functional enzyme activity, but lacking animal models, toxicology data, or any human in vivo evidence needed for clinical translation.

JUL 19, 2026 · JOURNAL ARTICLE

A Novel Genomic Strategy Against Hyperuricemia: CRISPR-CAS9-Mediated Restoration of Uricase Function from the Human Pseudogene

International Journal of Medical & Pharmaceutical Sciences

This is a mechanistic proof-of-concept study in cultured cells demonstrating CRISPR-mediated gene integration and enzymatic activity, not a clinical trial or in vivo validation; it raises the question of whether this approach could work therapeutically rather than answering it.

JUL 6, 2026 · REVIEW

From Four Pillars to Pharmacist-Led Optimization: A Narrative Review of Contemporary Heart Failure Pharmacotherapy and the Clinical Pharmacist's Role in Bridging the Guideline-to-Practice Gap

International Journal of Medical & Pharmaceutical Sciences

A narrative review synthesizing contemporary heart failure pharmacotherapy guidelines and defining the clinical pharmacist's role in implementation; evidence-based but not a trial and not practice-changing in itself.