BMC Psychiatry

JUL 31, 2026 · JOURNAL ARTICLE

Sleep quality, circadian rhythm disruption, functioning, and treatment adherence in major depression: a cross-sectional exploratory study

BMC Psychiatry

Cross-sectional exploratory study demonstrating associations among sleep, circadian rhythm, functioning, and adherence in depression, but lacking causal evidence, control group, or intervention testing to support practice change.

JUL 29, 2026 · JOURNAL ARTICLE

Treatment effects on sphingosine-1-phosphate and its receptors in major depressive disorder: implications for biomarkers

BMC Psychiatry

A single-centre, uncontrolled observational study with modest sample size (n=56 MDD patients) showing biomarker changes in response to treatment and diagnostic discrimination, but lacking a randomized comparator arm and requiring external validation before clinical deployment.

JUL 24, 2026 · JOURNAL ARTICLE

Sexual dysfunction and distress in patients with depressive disorders at a tertiary care hospital in Riyadh, Saudi Arabia: a cross-sectional study

BMC Psychiatry

Single-centre cross-sectional study using convenience sampling with no comparator group; establishes prevalence and associations but cannot infer causation and lacks the design rigour to guide clinical practice.