Pulmonary Hypertension Research and Treatments

SEP 2, 2026 · JOURNAL ARTICLE

Contemporary Evaluation and Management Strategies for Tricuspid Regurgitation

Critical Pathways in Cardiology a Journal of Evidence-based Medicine

A comprehensive narrative review synthesizing current literature on TR evaluation and management strategies, presenting expert consensus on classification, imaging, risk stratification, and therapeutic options without new primary data.

AUG 8, 2026 · REVIEW

VEGFR signalling and hemoptysis: mechanisms, critical appraisal of the evidence, and the double-edged role of VEGFR-2 inhibition — a narrative review

Egyptian Journal of Bronchology

A narrative review synthesizing mechanistic biology and case evidence that identifies a biologically plausible but clinically unproven hypothesis about VEGFR inhibition in hemoptysis, explicitly noting absence of controlled trials and the paradoxical risk of fatal hemorrhage.

JUL 28, 2026 · JOURNAL ARTICLE

Ralinepag for the treatment of pulmonary arterial hypertension (ADVANCE OUTCOMES): a randomised, double-blind, placebo-controlled phase 3 study

The Lancet

Phase 3 RCT demonstrates ralinepag significantly reduces clinical worsening in PAH (HR 0.45, p<0.0001) versus placebo in 687 patients with contemporary background therapy, with acceptable safety profile supporting clinical use.