Chronic Obstructive Pulmonary Disease (COPD) Research
7 developments in the corpus
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An uncontrolled animal model study demonstrating mechanistic features of obesity-asthma interaction; descriptive findings in a single species without human validation or clinical outcome data.
A narrative review synthesizing current evidence on long-term pulmonary sequelae of COVID-19, identifying reduced DLCO as the most prevalent finding and calling for standardized research and rehabilitation approaches.
Retrospective cohort study showing that inhaled COPD therapy associates with longer overall survival in advanced NSCLC, but the effect is confounded by ICI use and disappears in ICI-treated patients, confirming that ICI is the dominant prognostic factor.
A descriptive epidemiological analysis and modelling study synthesizing historical Global Burden of Disease data with Bayesian projections to 2050; no intervention trial, no novel mechanism, and projections rest on model assumptions not validated against future outcomes.
Prospective cohort study with moderate sample size (184 patients) showing MS prevalence and one-year mortality/exacerbation associations in COPD, but limited by single-centre design, lack of comparator arm, and reliance on observational follow-up rather than intervention.
A narrative review synthesizing evidence on sleep-disordered breathing and heart failure interactions, diagnostic approaches, and therapeutic options without presenting original data or a systematic meta-analysis.
This is a registered protocol for a future RCT; no results are presented, making it a pre-trial announcement of study design and intent rather than evidence of effectiveness.