Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
First-in-vivo evidence from a single small animal study without clinical validation, demonstrating mechanism but requiring confirmation in larger preclinical and human studies before clinical application.
A prospective cohort study with clear methodology and meaningful effect sizes in a clinically relevant population, but limited by single-centre design, lack of blinding, and reliance on a non-standard sarcopenia definition that requires external validation.
A comprehensive narrative review synthesizing evidence on geriatric mental disorder pathophysiology, management, and emerging approaches; provides clinical roadmap rather than new primary evidence.
A narrative review synthesizing current evidence on long-term pulmonary sequelae of COVID-19, identifying reduced DLCO as the most prevalent finding and calling for standardized research and rehabilitation approaches.
The International Journal of Neuropsychopharmacology
Retrospective analysis of 15 patients treated off-label with esketamine in routine clinical care, without control group, prospective protocol, or quantified outcome measures—early-phase evidence suggesting feasibility and benefit that requires controlled trials for confirmation.
A single-patient case report documenting clinical observations and imaging findings over time, without a comparator, control group, or quantified outcomes—raises diagnostic and prognostic questions but does not test a hypothesis rigorously.
Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Single case report describing clinical management and outcomes in a rare obstetric condition; documents feasibility of multidisciplinary psychiatric intervention but provides no comparative data or control group.
Observational study in real-world clinical setting demonstrates consistent associations between anticholinergic burden and multiple cognitive, functional, and mood domains across diagnostic groups, but cannot establish causation and lacks a comparator intervention.