Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
2 developments in the corpus
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A narrative review synthesizing preclinical evidence and limited clinical data suggesting the entopeduncular nucleus as a therapeutic target in psychiatric and sleep disorders, but lacking controlled trials or definitive human efficacy data.
This is a narrative review synthesizing mechanistic and clinical evidence on circadian rhythm disruption in MDD, offering conceptual synthesis and therapeutic direction without conducting systematic appraisal or reporting original trial data.