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This is a narrative review summarizing preclinical mechanistic evidence and emerging concepts about ferroptosis in pediatric cancer, without reporting original clinical trial data, efficacy comparisons, or definitive human outcomes.
A narrative review synthesizing mechanistic understanding and clinical evidence on TERT mutations in thyroid cancer, with expert consensus on risk stratification and emerging therapeutic strategies, but not a primary data study.
Preclinical study in animal and cell models with mechanistic endpoints; no human trials reported, limiting clinical applicability despite sound experimental design.
This is a comprehensive narrative review synthesizing current knowledge of AD genetics, pathways, and therapeutic targets rather than presenting original research evidence or clinical trial data.
Mechanistic study in cell and animal models demonstrating mutant p53-driven ferroptosis resistance and a potential combination therapeutic approach, but lacks clinical trial data and hard patient outcomes.
This is a computational and exploratory study integrating bioinformatics, network analysis, and preliminary in vitro work to identify candidate genes and a drug target in HCC, without controlled comparison or clinical outcome data.