Clusterin in Disease Pathology

AUG 7, 2026 · JOURNAL ARTICLE

Wogonoside alleviates metabolic dysfunction-associated steatohepatitis by modulating AMPK and xCT/GPX4 pathways to restrain lipid dysregulation and ferroptosis

Frontiers in Pharmacology

Preclinical study in animal and cell models with mechanistic endpoints; no human trials reported, limiting clinical applicability despite sound experimental design.

AUG 5, 2026 · JOURNAL ARTICLE

Decoding the Genetic Basis of Alzheimer's Disease: A Comprehensive Review of Key Causal and Risk Genes, Pathological Mechanisms, Convergent Pathways, and Emerging Therapeutic Targets

Middle East Research Journal of Medical Sciences

This is a comprehensive narrative review synthesizing current knowledge of AD genetics, pathways, and therapeutic targets rather than presenting original research evidence or clinical trial data.

JUL 23, 2026 · JOURNAL ARTICLE

Metabolic plasticity underlies ferroptosis resistance driven by mutant p53 in pancreatic ductal adenocarcinoma

Molecular Cancer

Mechanistic study in cell and animal models demonstrating mutant p53-driven ferroptosis resistance and a potential combination therapeutic approach, but lacks clinical trial data and hard patient outcomes.

JUL 17, 2026 · JOURNAL ARTICLE

In vitro and In vivo Based Multi-Target Therapy and Prognostic Bio-modeling inLiver Cancer

Current Pharmaceutical Design

This is a computational and exploratory study integrating bioinformatics, network analysis, and preliminary in vitro work to identify candidate genes and a drug target in HCC, without controlled comparison or clinical outcome data.