National Institute of Mental Health (NIMH)

SEP 9, 2026 · PHASE 2 TRIAL

Neurobiology of Suicide

ClinicalTrials.gov

This is a Phase 2 interventional trial still recruiting with no results posted; it describes a planned study of neurobiology and ketamine in suicide ideation but carries no outcome data.

AUG 18, 2026 · PHASE 1 TRIAL

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

ClinicalTrials.gov

Phase 1 imaging study in recruitment with no posted results; designed to detect COX-1 and COX-2 in MDD brains using novel radioligands, but efficacy or clinical utility remain undemonstrated.

AUG 18, 2026 · OBSERVATIONAL STUDY

The Psychobiology of Childhood Temperament

ClinicalTrials.gov

This is a completed observational registry record with no reported results; it describes study design and enrollment only, making it a preliminary report of planned work rather than evidence of efficacy or outcome.

AUG 17, 2026 · PHASE 1 TRIAL

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

ClinicalTrials.gov

This is a Phase 1 interventional registry record with no results posted; it describes a planned imaging study to measure cyclooxygenase elevation in neurodegenerative disease versus controls, but enrollment is ongoing and no outcomes have been reported.

AUG 17, 2026 · OBSERVATIONAL STUDY

Perimenopause-Related Mood and Behavioral Disorders

ClinicalTrials.gov

This is a completed observational registry record with no reported results; it describes study design and enrollment only, making it unsuitable for clinical inference until outcomes are published.

AUG 17, 2026 · PHASE 1 TRIAL

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

ClinicalTrials.gov

This is a Phase 1 mechanistic imaging study in active recruitment with no results posted; it aims to establish whether PDE4B is reduced in MDD brains using a novel radioligand, representing early-phase exploratory work.

AUG 14, 2026 · OBSERVATIONAL STUDY

Natural History of Depression, Bipolar Disorder and Suicide Risk

ClinicalTrials.gov

This is a clinical trial registry record describing an ongoing observational study with no results posted; it documents planned enrollment and outcome measures only.

AUG 13, 2026 · OBSERVATIONAL STUDY

Characterization and Treatment of Adolescent Depression

ClinicalTrials.gov

This is a registry record for an ongoing observational study with no results reported; recruitment is active and follow-up extends to two years, making this an early-stage characterization and treatment study without outcome data.