Immunotherapy

AUG 28, 2026 · JOURNAL ARTICLE

Store-operated calcium signaling modulators improve a dendritic cell-based vaccine against melanoma.

Oncoimmunology

Mechanistic study identifying a druggable pathway in dendritic cells using small molecules; lacks clinical efficacy data, human trials, or direct therapeutic outcome measurement.

AUG 24, 2026 · JOURNAL ARTICLE

Body mass index and dyslipidemia influence responses to anti-PD-1 immunotherapy in colorectal cancer.

Annals of Medicine

A retrospective single-centre cohort study identifies BMI and dyslipidemia as associations with improved PFS in anti-PD-1-treated CRC, supported by exploratory lipidomic profiling, but lacks a control arm and prospective design to establish causation or clinical utility.

AUG 17, 2026 · JOURNAL ARTICLE

The current role of immunotherapy in treating nasopharyngeal carcinoma.

Human Vaccines & Immunotherapeutics

This is a comprehensive narrative review synthesizing evidence on immunotherapy's current role in nasopharyngeal carcinoma management, drawing on completed and ongoing clinical trials to inform clinical practice and research priorities.

JUL 29, 2026 · JOURNAL ARTICLE

Protocol for a cohort study: evaluating the effect of neoadjuvant immunochemotherapy on intraoperative remifentanil consumption during IoC2-guided anesthesia in elderly patients with esophageal cancer.

Annals of Medicine

This is a protocol for a prospective observational cohort study not yet conducted; it describes planned methods and outcomes without results, establishing hypothesis-generating potential but lacking empirical evidence.

JUL 28, 2026 · JOURNAL ARTICLE

The evolution of cellular therapies in sarcoma: Breakthroughs, challenges, and future directions.

Human Vaccines & Immunotherapeutics

A narrative review summarizing the landscape of cellular therapies in sarcoma, reporting one FDA approval and describing early-stage investigational approaches without comparative efficacy data or quantified outcomes.

JUL 26, 2026 · JOURNAL ARTICLE

Characterization of persistent HPV-specific activated T cells in head and neck squamous cell carcinoma.

Oncoimmunology

Single-center mechanistic study with small sample size (n=4 for single-cell analysis) characterizing HPV-specific T-cell populations; functional validation of TCRs supports hypothesis but lacks clinical endpoint data or comparative outcome analysis.

JUL 15, 2026 · JOURNAL ARTICLE

Dietary intervention through bacterial-derived butyrate elicits anti-tumor activity and increases anti-PD-1 response.

Gut Microbes

Preclinical murine data with clinical correlative evidence in 117 NSCLC patients suggests dietary fiber and butyrate may enhance checkpoint inhibitor efficacy, but human intervention data are absent.

JUL 2, 2026 · JOURNAL ARTICLE

Biomimetic co-delivery nanoplatform overcomes CAF- and TAM-induced immunosuppression to augment therapeutic efficacy against triple-negative breast cancer.

International Journal of Pharmaceutics: X

Preclinical murine model study demonstrates nanoplatform remodels tumor microenvironment and enhances immune checkpoint blockade efficacy in triple-negative breast cancer.