AUG 20, 2026 · JOURNAL ARTICLE
Immune dysregulation in osteoarthritis: Mechanisms, biomarkers, and therapeutic opportunities.
Journal of Translational Autoimmunity
A peer-reviewed narrative review synthesizing mechanistic evidence and therapeutic literature to propose a framework for biomarker-guided stratification in osteoarthritis, without reporting original experimental or clinical trial data.
Reported
Global OA prevalenceover 500 million individuals
Annual economic burdenexceeding 300 billion
Projected prevalence increase by…approximately 40%