Lung Neoplasms

SEP 8, 2026 · JOURNAL ARTICLE

Thioredoxin reductase-1 facilitates cellular plasticity and stemness mediated by TGF-β1 in non-small cell lung cancer.

Cancer Biology & Therapy

Mechanistic study in cell lines and a mouse model identifying a pathway without clinical endpoint data or direct evidence of therapeutic benefit in humans.

AUG 19, 2026 · OBSERVATIONAL STUDY

Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization

ClinicalTrials.gov

This is a prospective observational pilot study not yet recruiting, with no results posted; it aims to establish feasibility and generate preliminary diagnostic performance estimates for a novel MRI protocol in lung lesion characterization.

AUG 13, 2026 · PHASE 1/2 TRIAL

Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer

ClinicalTrials.gov

This is a Phase 1/2 trial registry record with no posted results; the study has been terminated and no efficacy or safety outcomes are reported in this document.

JUL 20, 2026 · JOURNAL ARTICLE

Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin.

Cancer Biology & Therapy

In vitro study demonstrates reversal of cisplatin resistance in one cell line via ALDH and ABCC2 inhibition, requiring validation in additional models and clinical testing.