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A descriptive epidemiological analysis using secondary data from a global registry with projections to 2060, reporting trends and forecasts rather than testing an intervention or causal hypothesis, making it hypothesis-generating rather than confirmatory evidence.
Population-based cohort study with quantified screening rates and multivariable analysis confirms suboptimal colorectal cancer screening in both multiple sclerosis and general populations, with identified sociodemographic and clinical predictors.
British Journal of Healthcare and Medical Research
A small retrospective case series (n=6) describing a temporal association between GLP-1RA initiation and pouchitis in surgically altered anatomy; raises a hypothesis rather than establishing causation or providing quantified risk.
A bibliometric analysis mapping research trends and gaps in UC-depression comorbidity; useful for research direction but not clinical evidence on intervention efficacy or harm.
This is a narrative review synthesizing mechanistic theories and prior research on L. plantarum in IBD, presenting a conceptual framework rather than new empirical evidence or clinical trial data.
This is a narrative review synthesizing early-stage research on circRNAs in IBD pathogenesis; no primary experimental or clinical data are presented, and evidence remains exploratory with limited mechanistic validation.