Loading
Inflammatory Bowel Disease · Journal article
Multiple Sclerosis Journal · August 7, 2026
Reinforces what was already believed, rather than introducing something new.
This population-based cohort study of 63,509 individuals with multiple sclerosis and matched controls found that colorectal cancer screening coverage is suboptimal in both groups (41.2% in pwMS vs 42.4% in controls, p<0.001), with lower screening rates in older pwMS and among those with male sex or lower socioeconomic status. Qualitative data identified MS-related symptoms and psychological barriers as screening obstacles, offset by health system trust and prevention awareness as facilitators.
Population-based cohort study with matched controls and mixed-methods qualitative component. Individuals with multiple sclerosis aged 50–74 years and age-matched controls from the general population; 72.0% women, mean age 59.2 years.. Intervention: Colorectal cancer screening (type not specified). Compared with: Age-matched general population controls. n = 254,036. Not stated.
Annual CCS coverage was 41.2% in pwMS compared to 42.4% in controls (p<0.001) CCS was higher in pwMS aged 50–54 years (+1.5%, p<0.001) and lower in those ≥65 years (−1.6% to −6.2%, p<0.001) Male sex associated with lower CCS (odds ratio 0.90; 95% CI [0.86–0.93])
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
Clinicians caring for individuals with MS aged ≥65 years should heighten awareness of reduced screening uptake and proactively address MS-related barriers (motor/digestive symptoms, psychological disgust) and social determinants (socioeconomic status) to improve colorectal cancer screening participation. The findings suggest screening coverage remains suboptimal in both MS and general populations and requires targeted intervention.
Population-based cohort study with quantified screening rates and multivariable analysis confirms suboptimal colorectal cancer screening in both multiple sclerosis and general populations, with identified sociodemographic and clinical predictors.
As stated by the source record.
Quoted from the source exactly as published.
Clinicians caring for individuals with MS aged ≥65 years should heighten awareness of reduced screening uptake and proactively address MS-related barriers (motor/digestive symptoms, psychological disgust) and social determinants (socioeconomic status) to improve colorectal cancer screening participation. The findings suggest screening coverage remains suboptimal in both MS and general populations and requires targeted intervention.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Introduction: People with multiple sclerosis (pwMS) have a lower reported risk of colorectal cancer, which may reflect reduced access to colorectal cancer screening (CCS). Objectives: Compare CCS in pwMS and the general population and identify barriers and facilitators using mixed methods. Methods: In 2022–2024, PwMS aged 50–74 years and matched controls (3:1) were selected. Overall and age-stratified CCS coverage rates were computed. In pwMS, multivariable mixed-effects logistic models identified factors associated with CCS ⩾ 80%. Semi-structured interviews were carried out with 20 pwMS. Results: The cohort included 63,509 pwMS and 190,527 controls (72.0% women, mean age 59.2 years). Annual CCS coverage was 41.2% in pwMS and 42.4% in controls ( p < 0.001). In pwMS, CCS was higher in the 50–54 years (+1.5%, p < 0.001) and lower in the ⩾65 years group (−1.6% to −6.2%, p < 0.001). Male sex (odds ratio = 0.90; 95% CI = [0.86–0.93]) and lower ecological socioeconomic status (0.81 [0.76–0.86]) were associated with lower CCS, while disease-modifying therapies (1.12 [1.08–1.16]) and high healthcare use with higher CCS. Qualitative barriers included motor or digestive MS symptoms and feelings of disgust. Facilitators included health system trust and prevention awareness. Conclusion: CCS is lower among older pwMS and remains suboptimal in both pwMS and controls.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.