Retinoids in Leukemia and Cellular Processes

AUG 13, 2026 · JOURNAL ARTICLE

Clinical outcomes associated with NPM1 mutations in newly diagnosed acute myeloid leukemia

Cancer

Retrospective cohort analysis identifying prognostic factors and comparing outcomes across therapies in NPM1-mutated AML, with clear survival endpoints but limited by single-center design and observational methodology.

AUG 13, 2026 · JOURNAL ARTICLE

Targeting Cellular Senescence for Cancer Therapy

International Journal of Innovative Science and Research Technology

This is a narrative review summarizing biological mechanisms and therapeutic concepts without reporting original experimental data, clinical trials, or comparative efficacy evidence.

AUG 12, 2026 · JOURNAL ARTICLE

Fatal pulmonary thromboembolism associated with excessive nitrous oxide consumption over several weeks

International Journal of Legal Medicine

A single fatal case report proposing a mechanistic link between excessive nitrous oxide use, vitamin B12 deficiency, hyperhomocysteinemia, and pulmonary thromboembolism; raises a question rather than establishing causation.

AUG 8, 2026 · JOURNAL ARTICLE

Nuclear export inhibition activates TP53 pathways and is a potent therapeutic strategy in atypical teratoid rhabdoid tumors

Neuro-oncology Advances

Sound preclinical study with patient-derived models and in vivo validation showing XPO1 inhibition activates TP53 and reduces tumor burden, but lacks clinical trial data and human efficacy evidence.

AUG 7, 2026 · JOURNAL ARTICLE

Intracellular Retinoid-Binding Proteins (CRBP, CRALBP, CRABP) as Emerging Drug Targets in Retinal Disease

International Journal of Molecular Sciences

This is a narrative review article evaluating druggability of retinoid-binding proteins based on structural and biochemical evidence, raising questions about therapeutic potential rather than reporting clinical trial results or definitive efficacy data.