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Diogo Nery Maciel

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AUG 20, 2026 · JOURNAL ARTICLE

APPLICATION OF THE CRISPR-CAS9 SYSTEM IN BIRC5 GENE MODULATION IN TRIPLE-NEGATIVE BREAST CANCER: A REVIEW

Artefactum

A literature review synthesizing preclinical and mechanistic evidence on CRISPR-Cas9 for BIRC5 modulation in TNBC; raises therapeutic potential but acknowledges unresolved technical barriers and lack of clinical translation.

Hypothesis-GeneratingDiogo Nery Maciel CRISPR and Genetic Engineering Cancer Research and Treatments

Study details

DesignDescriptive and analytical literature review

InterventionCRISPR-Cas9-mediated BIRC5 gene editing (re…

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