Cancer, Lipids, and Metabolism

SEP 11, 2026 · JOURNAL ARTICLE

Lipid metabolism reprogramming: key mechanism of breast cancer endocrine therapy resistance

Frontiers in Oncology

This is a narrative review synthesizing mechanistic hypotheses about lipid metabolism in endocrine resistance; it raises questions and proposes connections rather than presenting original empirical evidence or clinical outcomes.

SEP 10, 2026 · JOURNAL ARTICLE

l-rhamnose suppresses triple-negative breast cancer via GSTM5-mediated ferroptosis

Discover Oncology

Mechanistic study in cell lines and mouse xenografts with a single candidate agent; no human data, no comparator arm, and no clinical endpoints reported.

SEP 10, 2026 · JOURNAL ARTICLE

Global Bibliometric Analysis of Post-Translational Modifications in Oral Squamous Cell Carcinoma

International Dental Journal

A descriptive bibliometric analysis mapping research landscape and trends rather than testing a clinical or mechanistic hypothesis; documents publication patterns and emerging themes without presenting primary experimental or clinical evidence.

SEP 9, 2026 · JOURNAL ARTICLE

Фиксированная комбинация розувастатина с эзетимибом в лечении пациентов высокого сердечно-сосудистого риска: мифы и реальность. Часть 2

Кардиология В Беларуси

This is a narrative review addressing clinical misconceptions about statin therapy and fixed-dose rosuvastatin–ezetimibe combinations, synthesizing existing evidence rather than reporting new empirical data.

SEP 9, 2026 · JOURNAL ARTICLE

Docosahexaenoic Acid Enhances the Cytotoxic Effects of Enzalutamide and the PARP Inhibitor in Castration-Resistant Prostate Cancer Cell Lines

International Journal of Molecular Sciences

In vitro mechanistic study in cancer cell lines showing DHA enhances cytotoxicity of existing drugs; no clinical evidence, animal models, or human data; raises questions about potential synergy requiring confirmation in vivo.

SEP 9, 2026 · JOURNAL ARTICLE

A SORT1-associated transcriptional signature links adipogenic plasticity, stemness and drug-resistance programs in 3D glioblastoma spheroids: dissection of ligand-dependent and ligand-independent arms

BMC Cancer

This is an exploratory mechanistic study in cultured glioblastoma cells using gene expression arrays and pharmacological perturbations to propose a model of SORT1 function; the authors explicitly state the model 'remains to be tested with direct functional assays', and no clinical outcome or animal validation is presented.

SEP 9, 2026 · REVIEW

Chinese medicine-based interventions in triple-negative breast cancer: mechanistic evidence, clinical findings, and translational challenges-a narrative review

Frontiers in Pharmacology

A narrative review mapping mechanistic evidence and clinical findings across heterogeneous Chinese medicine interventions in TNBC, acknowledging limited and methodologically weak clinical data and preclinical-only evidence for most mechanisms.

SEP 9, 2026 · JOURNAL ARTICLE

Glycolipid metabolic crosstalk in tumor immune evasion and therapeutic targeting

Discover Oncology

This is a narrative review proposing an integrated conceptual framework linking glycolipid metabolism to immune evasion, raising mechanistic questions rather than presenting empirical evidence from primary studies.