Muscle Physiology and Disorders

SEP 7, 2026 · JOURNAL ARTICLE

The Impact of Metabolic and Bariatric Surgery on Nutritional Status and Sarcopenia: A Narrative Overview of Underlying Mechanisms, Clinical Implications, and Prevention Strategies

Nutrients

This is a narrative review synthesizing current evidence on bariatric surgery's effects on muscle health and nutrition, providing clinical recommendations for a multidisciplinary approach to prevention and management.

SEP 7, 2026 · JOURNAL ARTICLE

Myosteatosis in type 1 diabetes: immunometabolic mechanisms, biomarkers, and therapeutic targets

Frontiers in Endocrinology

This is a narrative review synthesizing evidence from multiple disease models to generate a mechanistic framework for myosteatosis in T1D; the authors explicitly state direct mechanistic data from T1D skeletal muscle are scarce and the framework is deliberately hypothesis-generating, assembled substantially by inference from T2D, obesity, and ageing models.

AUG 14, 2026 · JOURNAL ARTICLE

Early physiological phenotypes and survival outcomes in advanced non-small cell lung cancer: a longitudinal study of dynamic muscle loss and functional decline

Frontiers in Oncology

Retrospective analysis with sound methodology (IPTW-adjusted, unsupervised clustering) identifying reproducible physiological phenotypes associated with survival outcomes in advanced NSCLC, but requiring prospective validation and lacking pre-specified primary endpoints.

AUG 11, 2026 · JOURNAL ARTICLE

Predictors of 12-Week Anamorelin Treatment Continuation in Gastrointestinal Cancer Cachexia: A Single-Center, Retrospective Study

Nutrition and Cancer

Single-center retrospective study identifying predictors of treatment completion rather than efficacy; useful for identifying barriers but lacks prospective validation and cannot establish causation.

AUG 11, 2026 · JOURNAL ARTICLE

EXERT-BCHC: a prospective study of exercise regimens after breast cancer to improve skeletal muscle hypertrophy and conditioning

Cardio-oncology

Small uncontrolled single-arm pilot study with no comparator group and no statistically significant primary outcomes; early-phase feasibility work in a specialized post-cancer population.

AUG 11, 2026 · REVIEW

Exercise-induced myokines and the muscle–tumor axis in obesity-driven gynecological cancers: a narrative review

Frontiers in Oncology

This narrative review synthesizes mechanistic evidence from disparate preclinical and observational studies to propose a theoretical framework linking exercise-induced myokines to tumor suppression in obesity-driven gynecological cancers, but does not report primary clinical trial data or direct human outcome evidence.

JUL 31, 2026 · JOURNAL ARTICLE

Phenotype rescue through the restoration of full-length dystrophin using CRISPR/Cas9 genome editing in Duchenne muscular dystrophy patient-derived iPSCs carrying the deletion of two exons

Genome Medicine

First-in-human demonstration of CRISPR/Cas9 correction of multi-exon DMD deletion in patient iPSCs with rescue of in vitro cardiac phenotypes, but limited to a single cell line, surrogate endpoints, and no animal or clinical translation yet.

JUL 27, 2026 · JOURNAL ARTICLE

Duchenne muscular dystrophy: from gene to gene-ius therapies

Skeletal Muscle

A comprehensive narrative review synthesizing current understanding of DMD pathophysiology, clinical management, and therapeutic landscape without presenting new original data or clinical trial results.