AUG 14, 2026 · JOURNAL ARTICLE
Early physiological phenotypes and survival outcomes in advanced non-small cell lung cancer: a longitudinal study of dynamic muscle loss and functional decline
Frontiers in Oncology
Retrospective analysis with sound methodology (IPTW-adjusted, unsupervised clustering) identifying reproducible physiological phenotypes associated with survival outcomes in advanced NSCLC, but requiring prospective validation and lacking pre-specified primary endpoints.
Reported
Sample size381
Monotherapy group153
Combination therapy group228