Disease

Metabolic Syndrome

6 developments in the corpus

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Everything in the corpus, newest first.

SEP 4, 2026 · INTERVENTIONAL STUDY

Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial

ClinicalTrials.gov

This is a clinical trial registry record with no results posted; the study is not yet recruiting and represents planned work only.

PreliminaryUniversity of Zadar Unhealthy Diet Mediterranean Diet Education

Reported

Planned sample size120

Follow-up duration12 months

Primary outcome: Mediterranean di…Baseline, 3 months, 6 months, 12 months

AUG 27, 2026 · JOURNAL ARTICLE

Self-efficacy in adopting health-promoting behaviors and metabolic health outcomes: A comparative analysis across adults populations.

Journal of Diabetes and Metabolic Disorders

Cross-sectional observational study with exploratory findings on self-efficacy and metabolic syndrome; authors explicitly state findings are exploratory and require longitudinal confirmation, limiting causal inference.

PreliminaryNeda Cheraghloo Reza Yari-Boroujeni Metabolic Syndrome

Reported

Sample size5947

Female proportion54.3%

MetS prevalence men37.21%

AUG 7, 2026 · OBSERVATIONAL STUDY

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

ClinicalTrials.gov

This is a registry record describing a planned observational study with no results reported; it documents study design and intended enrollment only.

PreliminaryNational Institute of Environmental Health Sciences (NIEHS)Metabolic Syndrome NCT01143480

Reported

Planned sample size725

Primary endpointsLevels of 6 cytokines (TNF alpha, IL-6, MIP…

Study visit duration45 to 60 minutes

AUG 6, 2026 · JOURNAL ARTICLE

Lifestyle modifications in individuals with blood pressure beyond treatment target despite pharmacological treatment: design and baseline characteristics of the MeDiPA randomised controlled trial.

Blood Pressure

This is a design paper reporting baseline characteristics of a small RCT (n=66) not yet reporting efficacy outcomes; the trial will generate evidence but no treatment effect data are presented.

PreliminaryMette Svendsen Hypertension Reza Ghiasvand

Reported

Age, mean (SD)59 (8) years

Female participants56%

Baseline office BP, mean (SD)137 (15)/90 (8) mmHg

JUL 28, 2026 · JOURNAL ARTICLE

Longitudinal comparative performance of triglyceride-glucose-related indices and estimated glucose disposal rate for predicting metabolic syndrome risk.

Journal of Diabetes and Metabolic Disorders

Prospective cohort with robust methodology (Cox models, time-dependent ROC, C-index, NRI/IDI) demonstrates TYG-WC as superior predictor of metabolic syndrome incidence with clinically meaningful effect size and excellent discrimination (C-index 0.83) across stratified subgroups.

Strong EvidenceSamia Abdi Salam Bennouar Abdelghani Bachir Cherif

Reported

Primary endpoint – aHR per SD1.44 (95% CI [1.24–1.66])

Risk at threshold >775.92.65-fold increased risk

Harrell's C-index0.83

JUL 24, 2026 · JOURNAL ARTICLE

Impact of lamiaceae plants on anthropometric indices in patients with metabolic syndrome: A systematic review and meta-analysis of randomized clinical trials.

Journal of Ethnopharmacology

Rigorous systematic review and meta-analysis of 20 RCTs with pre-registration, low risk of bias in majority of included studies, and high certainty of evidence for primary anthropometric outcomes (BMI, weight), though effect sizes are modest and direct body composition changes were not significant.

Strong EvidenceMarzieh Mojtahed Aziz A Fallah Leila Nasiri

Reported

Sample size2445

Number of included trials20

Allocation concealment unclear50%