Disease
4 developments in the corpus
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A single case report describing clinical response to tirzepatide in an adult with Prader–Willi syndrome and refractory diabetes; lacks comparison group, quantified outcomes, and generalizability.
AUG 14, 2026 · JOURNAL ARTICLE
The Journal of Physiology
Mechanistic study in a mouse model proposing neuronal mechanisms for PWS phenotype; lacks human validation and clinical outcome measures.
AUG 11, 2026 · JOURNAL ARTICLE
Frontiers in Endocrinology
This is a narrative commentary synthesizing existing evidence to recommend early rhGH initiation in PWS, not reporting new primary data or a systematic review with meta-analysis.
AUG 11, 2026 · JOURNAL ARTICLE
The Journal of Clinical Endocrinology & Metabolism
Large descriptive cohort establishing clinical phenotype and proposing a novel diagnostic scoring system, but lacking a control group, prospective validation of the score, or powered comparison of outcomes.