Hepatocellular Carcinoma Treatment and Prognosis

SEP 7, 2026 · JOURNAL ARTICLE

From mechanisms to practice: risk management and multidisciplinary decision-making for systemic treatment-related liver injury in HBV-associated hepatocellular carcinoma

Frontiers in Pharmacology

A structured narrative review synthesizing pathophysiological mechanisms, drug hepatotoxicity profiles, and a proposed clinical management framework for treatment-related liver injury in HBV-associated HCC, intended to guide clinical decision-making.

SEP 7, 2026 · JOURNAL ARTICLE

Focused Ultrasound Therapies for Brain, Liver, Prostate, and Breast Cancer Applications: Clinical Evidence and Future Directions

Cancers

A narrative review synthesizing early clinical trial data on an emerging technology without meta-analysis, formal quality assessment, or definitive efficacy endpoints; represents current state of evidence rather than practice-changing guidance.

SEP 1, 2026 · JOURNAL ARTICLE

Changing epidemiology and etiology of hepatocellular carcinoma in Europe: implications for clinical practice and health policy

The Lancet Regional Health - Europe

A narrative synthesis of epidemiological trends and clinical management implications for HCC in Europe, intended to inform practice and policy rather than report a primary research finding.

SEP 1, 2026 · JOURNAL ARTICLE

Hepatocellular carcinoma surveillance in Europe: challenges and lessons from global practice

The Lancet Regional Health - Europe

A narrative review synthesizing surveillance recommendations, implementation challenges, and emerging approaches across geographies, offering expert consensus on HCC screening practice rather than primary evidence of clinical efficacy.

AUG 15, 2026 · JOURNAL ARTICLE

Liver Transplantation Following Hepatocellular Carcinoma Rupture and Long-Term Immunotherapy: A Case Report

Journal of Gastrointestinal Cancer

A single case report of advanced HCC with rupture treated with combination immunotherapy and successfully transplanted; demonstrates feasibility but lacks comparator, control group, and generalizability needed to establish efficacy or change practice.

AUG 14, 2026 · JOURNAL ARTICLE

Identification of a stemness-related prognostic signature and functional characterization of NCAPG in hepatocellular carcinoma

BMC Gastroenterology

A multi-algorithm machine learning signature study with external validation across four datasets and functional validation of a candidate gene, showing clear prognostic separation but limited by retrospective cohort design and surrogate endpoints rather than prospective clinical outcomes.

AUG 14, 2026 · JOURNAL ARTICLE

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation

This is a narrative review summarizing preclinical and in vitro organoid technologies without reporting original empirical data, clinical outcomes, or comparative efficacy in humans.

AUG 13, 2026 · JOURNAL ARTICLE

Prognostic Value of Liver Function and Tumor Burden Scores in Patients with HCC After Transarterial Radioembolization – Retrospective Single Center Analysis

Journal of Gastrointestinal Cancer

Single-centre retrospective study with modest sample size identifies ALBI score as prognostic for survival after TARE, but lacks prospective design, external validation, and mechanistic insight into clinical benefit.