Researcher

Yan Zhang

Department of Orthopedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

2 developments in the corpus

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Latest

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JUL 27, 2026 · JOURNAL ARTICLE

Comorbid mechanisms of psoriasis and mental disorders: an analysis of inflammatory and psychosocial interactions

Frontiers in Psychiatry

A narrative literature review synthesizing mechanistic pathways between psoriasis and psychiatric comorbidity; raises integrated treatment questions but does not present original empirical data or controlled evidence comparing outcomes.

Hypothesis-GeneratingTryptophan and Brain Disorders Yan Zhang Dermatology and Skin Diseases

Study details

DesignNarrative literature review

InterventionLiterature review of biological, neuroendoc…

JUN 22, 2026

KIF18A inhibitor prevents chromosomally unstable osteosarcoma growth by activating spindle assembly checkpoint.

Cancer Biology & Therapy

Preclinical cell-line and xenograft data showing anti-tumor activity of a KIF18A inhibitor in osteosarcoma models without human trial evidence.

PreliminaryYan Zhang Xenograft Model Antitumor Assays Spindle Assembly Checkpoint

Study details

DesignPreclinical cell-line and xenograft study

InterventionKIF18A knockout or KIF18A inhibitor AM-1882

ComparatorParental SJSA1 cells, chemotherapeutic drug…