Theoretical and Natural Science

SEP 8, 2026 · JOURNAL ARTICLE

Gut Microbiome Control of Tumor Immune Checkpoint Inhibitor Response: Mechanistic Insights and Clinical Translation

Theoretical and Natural Science

This is a mechanistic review summarizing proposed pathways by which microbiota may influence ICI response, raising questions for future investigation rather than reporting a primary empirical result or clinical trial outcome.

SEP 8, 2026 · JOURNAL ARTICLE

Targeting LZK in Oral Squamous Cell Carcinoma: A Review of Local PROTAC Delivery via Dissolving Microneedles

Theoretical and Natural Science

This is a narrative review proposing a theoretical therapeutic strategy combining LZK-PROTAC degradation with dissolving microneedle delivery for OSCC; no clinical trial data, preclinical evidence, or mechanistic validation is presented.

SEP 8, 2026 · JOURNAL ARTICLE

Nanocarrier-Mediated Gene Editing for Improved Tumour Therapeutic Efficacy

Theoretical and Natural Science

A narrative review of preclinical literature synthesizing nanocarrier design and CRISPR delivery mechanisms, raising research directions rather than reporting original empirical evidence or clinical outcomes.

SEP 8, 2026 · JOURNAL ARTICLE

Effects of Lactylation in Cancer Progression

Theoretical and Natural Science

A narrative review of mechanistic pathways linking protein lactylation to cancer phenotypes; raises questions about therapeutic potential but reports no empirical data, effect sizes, or clinical outcomes.

AUG 17, 2026 · JOURNAL ARTICLE

A Literature Review of Recent Advances in Cell Therapy for Diabetes Mellitus

Theoretical and Natural Science

A literature review summarizing clinical development, technical principles, and experimental results of cell therapy approaches for diabetes, offering a reference for research and clinical translation rather than reporting primary evidence.

AUG 17, 2026 · JOURNAL ARTICLE

How Cancer Cells Exploit Unfolded Protein Response Signaling for Survival, Metastasis, and Therapy Resistance

Theoretical and Natural Science

This is a narrative review synthesizing mechanistic understanding of how cancer cells exploit UPR signaling; it raises questions about therapeutic opportunity rather than testing efficacy in a clinical or experimental design.

AUG 11, 2026 · JOURNAL ARTICLE

Feline Mammary Tumors Across Five Countries: A Comparative Literature Review

Theoretical and Natural Science

A narrative literature review that raises comparative epidemiological questions about feline mammary tumors across countries without presenting original data, quantitative synthesis, or evidence of systematic methodology.