Regenerative Therapy

OCT 22, 2026 · JOURNAL ARTICLE

Protocol for a phase I/II, open-label, single-arm trial of autologous chemically induced liver progenitor (CLiP) cell transplantation in patients with decompensated cirrhosis

Regenerative Therapy

Introduction Decompensated cirrhosis is associated with a poor prognosis and limited therapeutic options for patients who are not candidates for liver transplantation. Although var

SEP 19, 2026 · JOURNAL ARTICLE

Genetically engineered hypoimmunogenic iPSCs: Strategies and considerations for clinical applications.

Regenerative Therapy

Induced pluripotent stem cell (iPSC)-based therapies are rapidly advancing toward clinical implementation, with increasing numbers of trials and approvals for allogeneic iPSC-deriv

SEP 19, 2026 · JOURNAL ARTICLE

Pilot study of Wilms tumor 1-targeted human platelet lysate-induced antigen-presenting cells in advanced solid cancer patients

Regenerative Therapy

Introduction For the wide implementation of dendritic cell-based cancer immunotherapy, a clinical phase I study was conducted to explore its safety and tolerability using Wilms’ tu

AUG 24, 2026 · JOURNAL ARTICLE

Advanced therapy medicinal products in Saudi Arabia: Regulation and development.

Regenerative Therapy

A narrative review synthesizing regulatory frameworks, guidelines, and implementation status of ATMPs in an emerging market; informs policy and institutional strategy rather than clinical practice or mechanistic evidence.

JUL 29, 2026 · JOURNAL ARTICLE

Host-state biomarkers and clinical factors for stratification and optimization of cell therapy trials in chronic limb-threatening ischemia: A review.

Regenerative Therapy

A structured narrative review synthesizing evidence on host-state biomarkers and clinical factors for CLTI cell therapy trial design, proposing a conceptual framework for prognostic stratification rather than reporting new primary efficacy data.

JUL 4, 2026 · JOURNAL ARTICLE

CXCL12-abundant reticular cell lineage is the key source of endosteal osteoblasts and adipocytes in adult bone marrow.

Regenerative Therapy

This is a mechanistic lineage-tracing study in genetically modified mice that identifies CAR cells as a source of endosteal osteoblasts and adipocytes, but lacks clinical outcome data, human validation, or therapeutic intervention testing needed to guide practice.

JUN 15, 2026 · REVIEW/PERSPECTIVE

Therapeutic frontiers in ALS: iPSC-based drug discovery, cell therapy, and gene therapy-Advances through 2026.

Regenerative Therapy

Narrative review synthesizing therapeutic developments across multiple ALS modalities without original comparative efficacy data.