Drug or technology

Cell Therapy

2 developments in the corpus

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JUL 29, 2026 · JOURNAL ARTICLE

Host-state biomarkers and clinical factors for stratification and optimization of cell therapy trials in chronic limb-threatening ischemia: A review.

Regenerative Therapy

A structured narrative review synthesizing evidence on host-state biomarkers and clinical factors for CLTI cell therapy trial design, proposing a conceptual framework for prognostic stratification rather than reporting new primary efficacy data.

Expert GuidanceCell Therapy Hiroshi Sunami Naoki Matsuura

Reported

Prevalence of no-option CLTI20%–30%

1-year major-amputation rate10%–40%

1-year mortality rate20%–25%

JUN 15, 2026 · REVIEW/PERSPECTIVE

Therapeutic frontiers in ALS: iPSC-based drug discovery, cell therapy, and gene therapy-Advances through 2026.

Regenerative Therapy

Narrative review synthesizing therapeutic developments across multiple ALS modalities without original comparative efficacy data.

Expert GuidanceCell Therapy Shinichi Takahashi Hideyuki Okano

Reported

Proportion of sporadic ALS casesapproximately 90%