Kinases and Phosphatases

SEP 10, 2026 · JOURNAL ARTICLE

Role of Protein Kinase C in Insulin Resistance and Metabolic Syndrome

Kinases and Phosphatases

A mechanistic review examining PKC's role in insulin resistance and metabolic syndrome that raises questions about signaling pathways rather than reporting primary experimental evidence or clinical outcomes.

SEP 8, 2026 · JOURNAL ARTICLE

Emerging Roles of TMEM97/Sigma-2 Receptor in Breast Cancer Endocrine Resistance: Links to mTOR Signaling and Cholesterol Metabolism

Kinases and Phosphatases

This is a mechanistic review summarizing preclinical evidence linking TMEM97/sigma-2 receptor to endocrine resistance pathways; the source explicitly states evidence remains preclinical and further investigation is needed.

AUG 18, 2026 · JOURNAL ARTICLE

Regulation of Extracellular HMGB-1 Alarmin Levels by CIGB-300 Anticancer Peptide In Vitro and In Vivo

Kinases and Phosphatases

Early mechanistic work combining in vitro cell lines with exploratory Phase I data, investigating a biomarker association rather than clinical outcomes; needs confirmatory studies in larger patient cohorts.