Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
This is a mechanistic review summarizing preclinical evidence linking TMEM97/sigma-2 receptor to endocrine resistance pathways; the source explicitly states evidence remains preclinical and further investigation is needed.
This is a narrative review synthesizing mechanistic evidence and observational associations of the prorenin receptor across multiple diseases, without reporting primary clinical trial data or definitive causal evidence.