Objective To review the mechanism of action, clinical efficacy, safety considerations and future development of bispecific T-cell engagers (BTCEs) in solid tumors. Data sources A l
Objective Medication safety is an underdeveloped dimension of pediatric oncology survivorship despite persistent medication exposure after cancer therapy. This review synthesizes e
IntroductionMetastasis occurs in almost 50% of patients with uveal melanoma. In patients who are HLA-A*02:01 positive, first line treatment is the Immune mobilizing monoclonal T ce
Introduction Trastuzumab is a humanized HER2 targeting monoclonal antibody, and it is indicated for the treatment of various HER-2-positive cancers, including breast and gastrointe
Introduction This study aimed to systematically evaluate the association between adverse drug reactions, medication adherence, and outpatient treatment outcomes among women with br
Objective To critically review the current pharmacologic treatment landscape for epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC), focusing on clin
Retrospective cohort study of 330 patients reporting an obesity paradox in mHSPC; confirms known associations but BMI did not retain independent significance in multivariate analysis, limiting practice implications.
High-quality meta-analysis of 23 Phase II/III RCTs (n=8797) demonstrating clinically meaningful improvements in DFS, OS, and pCR with carboplatin-containing chemotherapy in TNBC, with rigorous pooling and quantified safety trade-offs.