Journal of Agricultural and Food Chemistry

OCT 20, 2026 · JOURNAL ARTICLE

Oral Protein Fibril Microgels with Gastric Stability and Intestinal Targeting Enhance Capsaicin Bioavailability for Effective Obesity Prevention

Journal of Agricultural and Food Chemistry

Abstract To address the susceptibility of protein fibrils to pepsin degradation, this study proposed a fibril-to-microgel hierarchical assembly strategy, where flexible whey protei

OCT 10, 2026 · JOURNAL ARTICLE

Lactobacillus gasseri LG-G12 Alleviates High-Fat Diet-induced Obesity through Gut Microbiota-Bile Acid Axis

Journal of Agricultural and Food Chemistry

Abstract The role of probiotics in weight management remains controversial. In this study, we found that Lactobacillus gasseri LG-G12 exhibits gut colonization capacity and metabol

OCT 8, 2026 · JOURNAL ARTICLE

Natural Polysaccharides in Health and Targeting TGF-β/Smad Signaling Therapy in Chronic Diseases

Journal of Agricultural and Food Chemistry

Abstract Chronic diseases including cardiovascular disorders, cancers, diabetes and organ fibrosis are major global causes of mortality. The transforming growth factor-β (TGF-β)/su

OCT 2, 2026 · JOURNAL ARTICLE

Quercetin Ameliorates Cognitive Impairment in Obese Mice by Activating the PI3K/AKT/GSK3β Signaling Pathway via the Microbiota–Gut–Brain Axis

Journal of Agricultural and Food Chemistry

Abstract Obesity and its associated insulin resistance are important risk factors for cognitive impairment. In this study, a 10-week C57BL/6 mouse model was established to investig

SEP 28, 2026 · JOURNAL ARTICLE

The Bidirectional Interaction between Ginsenosides and Intestinal Flora and Its Regulatory Mechanism of Antiobesity Effects

Journal of Agricultural and Food Chemistry

Abstract Obesity, a major global health challenge, is closely linked to energy imbalance and gut microbiota disorders, and the key bioactive compounds in ginseng─ginsenosides─have

AUG 17, 2026 · JOURNAL ARTICLE

Arbutin ReshapesIntestinal Microbiota to AmeliorateLipid Metabolic Dysfunction and Inflammation

Journal of Agricultural and Food Chemistry

A mechanistic study in obese mice demonstrating arbutin-induced metabolic and inflammatory improvements through microbiota modulation, supported by functional validation via antibiotic depletion and FMT, but limited to animal model without human efficacy data.

AUG 11, 2026 · JOURNAL ARTICLE

Dynamic Responses of α-Amylase to Dietsand Their Impact on Metabolic Health: Insights from a Novel NoninvasiveImaging

Journal of Agricultural and Food Chemistry

Early-phase preclinical study demonstrating a novel imaging probe in mice with exploratory findings on diet-enzyme relationships; lacks human validation, clinical endpoints, and comparative controls.

AUG 10, 2026 · JOURNAL ARTICLE

Kaempferol CounteractsObesity and Impairs Adipogenesisby Suppressing PI3K/AKT/GSK3β-Mediated Mitotic Clonal Expansionand Attenuating Adipose Tissue Fibrosis

Journal of Agricultural and Food Chemistry

Mechanistic study in cell culture and diet-induced obesity model with surrogate endpoints; establishes a biological pathway but lacks human evidence and hard clinical outcomes needed to guide practice.